Bivariate analysis of categorical variables of interest: relationship between clinical response and patient satisfaction

Bivariate analysis of categorical variables of interest: relationship between clinical response and patient satisfaction

Carlos H. Mora-Cevallos 1 , Valeria González-Sacoto 2 , Carmen Ambroj-Navarro 1 , Beatriz Mateo-Hernández 3 , Benjamín Blasco-Beltrán 1

1 Servicio de Urología, Hospital Clínico Universitario Lozano Blesa, Zaragoza, España; 2 Servicio de Endocrinología, Hospital de Barbastro, Huesca, España; 3 Servicio de Enfermería en Urología, Hospital Clínico Universitario Lozano Blesa, Zaragoza, España

*Correspondence: Carlos H. Mora-Cevallos. Email: carlos_mc12@msn.com

Abstract

Objective: To evaluate the efficacy and safety of intravesical botulinum toxin type A (BoNT-A) injections in an outpatient setting under local anesthesia in patients with refractory overactive bladder (OAB).

Method: Retrospective observational study on 52 patients with refractory OAB, both idiopathic and neurogenic. Patients with idiopathic OAB received 100 units of BoNT-A, while those with neurogenic OAB were administered 200 units. Pain was assessed using the visual analog scale (VAS), and symptoms were evaluated with the ICIQ-SF questionnaire. Follow-ups were conducted at 1, 6, and 9 months.

Results: At 30 days, 57.7% of patients demonstrated clinical improvement. At 6 months, 48.1% maintained the improvement, while 42.3% sustained it at 9 months. The mean ICIQ-SF score significantly decreased from 18 to 7.25 points (p < 0.001). During the procedure, 90% of patients reported pain levels < 2 on the VAS. The most common complication was hematuria, observed in 34.6% of cases.

Conclusions: Intravesical BoNT-A injections under local anesthesia represent a safe and effective option for the treatment of refractory OAB, providing positive clinical outcomes and high patient satisfaction.

Keywords: Overactive bladder. Botulinum toxin type A. Intravesical injections.

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